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Gynecologic Cancer InterGroup (GCIG) Consensus Review for Ovarian Sex Cord Stromal Tumors
- Source :
- International Journal of Gynecologic Cancer. 24:S42-S47
- Publication Year :
- 2014
- Publisher :
- BMJ, 2014.
-
Abstract
- Sex cord stromal tumors (SCST) are rare cancers of the ovarian area in adults. They constitute a heterogeneous group of tumors that develop from the sex cords and the ovarian stroma. These tumors are detected typically at an early stage, and they may recur as late as 30 years after the initial treatment. Because 70% of the patients present with stage I tumors, surgery represents the most important therapeutic arm. There are no data to support any kind of postoperative adjuvant treatment for patients with stage IA or IB SCSTs, given the indolent nature of these neoplasms and the overall good prognosis. The long natural history of the disease may lead to repeated surgical procedure should a relapse occurs. Platinum-based chemotherapy is currently used for patients with advanced stage SCSTs or recurrent disease, with an overall response rate of 63% to 80%. The indolent nature of SCSTs with the tendency for late recurrence requires long-term follow-up.
- Subjects :
- Adult
Oncology
medicine.medical_specialty
Consensus
Stromal cell
Bevacizumab
medicine.medical_treatment
Disease
Medical Oncology
Internal medicine
medicine
Humans
Sex Cord-Gonadal Stromal Tumors
Combined Modality Therapy
Repeated Surgical Procedure
Stage (cooking)
Societies, Medical
Ovarian Neoplasms
Chemotherapy
business.industry
Obstetrics and Gynecology
Natural history
sex cord stromal tumors, ovarian tumors, gynecologic cancer intergroup post-operative adjuvant treatment
Practice Guidelines as Topic
Female
business
medicine.drug
Subjects
Details
- ISSN :
- 15251438 and 1048891X
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- International Journal of Gynecologic Cancer
- Accession number :
- edsair.doi.dedup.....92c487e021ffde7311d220c0c7868f4f