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Terpenoids, essential oil composition, fatty acid profile, and biological activities of Anatolian Salvia fruticosa Mill
- Source :
- Volume: 37, Issue: 4 619-632, Turkish Journal of Chemistry
- Publication Year :
- 2014
- Publisher :
- TÜBİTAK, 2014.
-
Abstract
- Topcu, Gulacti/0000-0002-7946-6545; Ozturk, Mehmet/0000-0001-8932-4535; Topcu, Gulacti/0000-0002-7946-6545 WOS: 000321817800011 The hexane and dichloromethane extracts, obtained by re-extraction of the methanol extract of Salvia fruticosa Mill., afforded 7 diterpenoids (carnosol, carnosic acid, carnosic acid 12-methyl ether, rosmadial, isorosmanol, ferruginol, and manool), 4 triterpenoids (alpha-amyryltetracosanoate, oleanolic acid, ursolic acid, and erythrodiol), a steroid (3-acetylsitosterol), and a flavone (salvigenin). The galls (apples) of the collected plant were separately extracted with hexane to afford fatty acids composed mainly of oleic acid (29%), palmitoleic acid (29%), and stearic acid (23.20%), which exhibited high anticholinesterase activity, particularly against BChE. The essential oil, obtained from the aerial parts of the plant, exhibited high AChE inhibitory activity, consisting of mainly 1,8-cineol (58.89%). The antioxidant activity according to 6 complementary tests and anticholinesterase potential of the methanol extracts and triterpenoids alpha-amyryltetracosanoate, oleanolic acid, ursolic acid, and sitosterol acetate were also investigated, and methanol extract exhibited the highest antioxidant and anticholinesterase activity, surpassing the other tested extracts and pure compounds. Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK - TBAG - 107T592] This work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK - TBAG - 107T592).
- Subjects :
- Mühendislik
Anticholinesterase
law.invention
chemistry.chemical_compound
Salvia fruticosa
Engineering
Ursolic acid
law
Palmitoleic acid
Organic chemistry
Lamiaceae,Salvia fruticosa,secondary metabolites,abietane diterpenoids,triterpenoids,essential oil,fatty oil,antioxidant,anticholinesterase
Secondary Metabolites
Abietane Diterpenoids
Oleanolic acid
Essential oil
Fatty Oil
Chromatography
Lamiaceae
biology
Carnosic acid
General Chemistry
Triterpenoids
biology.organism_classification
Essential Oil
Oleic acid
chemistry
Stearic acid
Salvia Fruticosa
Antioxidant
Subjects
Details
- Language :
- English
- ISSN :
- 13000527 and 13036130
- Database :
- OpenAIRE
- Journal :
- Volume: 37, Issue: 4 619-632, Turkish Journal of Chemistry
- Accession number :
- edsair.doi.dedup.....9274dc13d31a430e882b45658821a196