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A Seven-Month Survival of a Calf with an Artificial Heart Designed for Human Use
- Source :
- Artificial Organs. 5:125-131
- Publication Year :
- 1981
- Publisher :
- Wiley, 1981.
-
Abstract
- A Jarvik-7 type of pneumatic artificial heart, which was specifically designed to fit the anatomy and hemodynamic requirements of human patients, was implanted in a calf in an experiment to test the hemodynamic performance of the artificial heart. The experiment lasted for 221 days, longer than any animal had ever lived without its natural heart, despite the fact that the calf increased its body weight to 171 kg. The calf showed typical signs of low cardiac output before its death, but the direct cause of death was intestinal bleeding. At autopsy, it was discovered that the low cardiac output was due to severe pannus around the left inflow valve, as diagnosed earlier by changes in the pneumatic pressure wave form.
- Subjects :
- Male
medicine.medical_specialty
Cardiac output
Wave form
Biomedical Engineering
Medicine (miscellaneous)
Pannus
Hemodynamics
Bioengineering
Autopsy
Heart, Artificial
law.invention
Biomaterials
Human use
Heart Rate
law
Artificial heart
Internal medicine
medicine
Animals
Cardiac Output
Cause of death
business.industry
Heart
General Medicine
medicine.disease
Surgery
Surgical Procedures, Operative
Heart Function Tests
Cardiology
Cattle
business
Subjects
Details
- ISSN :
- 15251594 and 0160564X
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Artificial Organs
- Accession number :
- edsair.doi.dedup.....92504cf8491a86c1d7a176176574f277