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Using STN DBS and medication reduction as a strategy to treat pathological gambling in Parkinson's disease
- Source :
- Parkinsonismrelated disorders. 13(6)
- Publication Year :
- 2006
-
Abstract
- We describe two patients with Parkinson's disease (PD) who developed clinical criteria of pathological gambling addiction in the setting of increased dopamine replacement therapy (levodopa and dopamine agonist medications). The second patient showed also signs of dopamine dysregulation syndrome, with an addiction to dopaminergic medication. Neither patients responded to the standard therapy for gambling behavior, but dramatically improved after bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) and early postoperative withdrawal of dopaminergic therapy. The possible therapeutic role of subthalamic nucleus deep brain stimulation (STN-DBS) on such a disabling behavior needs to be investigated prospectively.
- Subjects :
- Adult
Male
medicine.medical_specialty
Levodopa
Deep brain stimulation
Parkinson's disease
medicine.medical_treatment
Deep Brain Stimulation
Dopamine agonist
Pramipexole
Subthalamic Nucleus
Punding
medicine
Humans
Benzothiazoles
Dopamine dysregulation syndrome
business.industry
Dopaminergic
Parkinson Disease
Middle Aged
medicine.disease
nervous system diseases
Subthalamic nucleus
surgical procedures, operative
Neurology
Anesthesia
Dopamine Agonists
Gambling
Physical therapy
Neurology (clinical)
Geriatrics and Gerontology
business
medicine.drug
Subjects
Details
- ISSN :
- 13538020
- Volume :
- 13
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Parkinsonismrelated disorders
- Accession number :
- edsair.doi.dedup.....9243c562a29f80afb50e0a0334821c93