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The human immunoglobulin VH repertoire

Authors :
Graham P. Cook
Ian M. Tomlinson
Source :
Immunology Today. 16:237-242
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

A complete map of the human immunoglobulin VH locus on chromosome 14 has recently been constructed. The locus is 1100kb in length and contains 51 functional VH segments interspersed amongst a similar number of pseudogenes. Here, Graham Cook and Ian Tomlinson review the organization of the locus, its polymorphism and the repertoire it encodes.

Subjects

Subjects :
Chromosomes, Human, Pair 14
Genetics
Polymorphism, Genetic
Repertoire
Pseudogene
Immunology
Immunoglobulin Variable Region
Chromosome Mapping
Chromosome
Locus (genetics)
Biology
Human immunoglobulin
Humans
Pseudogenes

Details

ISSN :
01675699
Volume :
16
Database :
OpenAIRE
Journal :
Immunology Today
Accession number :
edsair.doi.dedup.....9242becc87b5fc0052482b1393dbd3c8
Full Text :
https://doi.org/10.1016/0167-5699(95)80166-9
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