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Health-Related Quality of Life and Health Resource Utilization in Patients with Primary Immunodeficiency Disease Prior to and Following 12 Months of Immunoglobulin G Treatment
- Source :
- Journal of Clinical Immunology
- Publication Year :
- 2015
-
Abstract
- Purpose Health-related quality of life (HRQOL) has not been examined in patients with predominant antibody deficiency both pre- and post-immunoglobulin G (IgG) treatment initiation. HRQOL and health resource utilization (HRU) were assessed in newly diagnosed patients with primary immunodeficiency disease (PIDD) pre- and 12 months post-IgG treatment initiation. Methods Adults (age ≥18 years) completed the 36-item Short Form Health Survey, version 2; pediatric patients (PP)/caregivers completed the Pediatric Quality of Life Inventory (PedsQL). Scores were compared with normative data from the US general population (GP) and patients with other chronic conditions (OCC). Results Seventeen adult patients (APs), 8 PPs, and 8 caregivers completed baseline assessments. APs had significantly lower baseline mean physical component summary scores versus GP (37.4 vs 50.5, p
- Subjects :
- 0301 basic medicine
Adult
Male
Pediatrics
medicine.medical_specialty
Population
Immunology
Disease
Immunoglobulin G
03 medical and health sciences
0302 clinical medicine
Quality of life
Surveys and Questionnaires
medicine
Back pain
Immunology and Allergy
Humans
Medical prescription
education
Child
pediatric quality of life inventory (PedsQL)
education.field_of_study
Primary immunodeficiency
biology
business.industry
Immunologic Deficiency Syndromes
Infant, Newborn
Immunoglobulins, Intravenous
Infant
Middle Aged
Patient Acceptance of Health Care
health resource utilization, short form health survey (SF-36)
medicine.disease
antibody deficiency
health-related quality of life
030104 developmental biology
Child, Preschool
biology.protein
Quality of Life
Health Resources
Female
Original Article
medicine.symptom
business
Psychosocial
030215 immunology
Subjects
Details
- ISSN :
- 15732592
- Volume :
- 36
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of clinical immunology
- Accession number :
- edsair.doi.dedup.....922fa84a23320b3dbd3bb448e91ffe15