Additional file 12 of Immuno-genomic classification of colorectal cancer organoids reveals cancer cells with intrinsic immunogenic properties associated with patient survival

Additional file 12 Supplementary Fig. 11. (A) Pathway analysis using tissue RNA sequence data based on the tumor immune microenvironment (TIM) class. (B, C) Significance of Wnt/β-catenin signaling pathway in the non-immunogenic group using GSVA analysis (Wilcoxon rank-sum test). (D) APC mutation status based on the TIM class. (E) Significance of biallelic APC mutation and TIM class (Fisher’s exact test). (F) Expression of target genes belonging to the Wnt/beta-catenin pathway (Wilcoxon rank-sum test).