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NSTI Organisms and Regions: A Multicenter Study From the American Association for the Surgery of Trauma
- Source :
- The Journal of surgical research. 243
- Publication Year :
- 2019
-
Abstract
- BACKGROUND Conflicting data on the microbiology and epidemiology of necrotizing soft tissue infections (NSTIs) appear to stem from the heterogeneity in microbiology observed in regions across the United States. Our goal was to determine current differences in organism prevalence and outcomes for NSTI and non-necrotizing severe soft tissue infections across the United States. We hypothesized that there were geographical differences in organism prevalence that would lead to differences in outcomes. MATERIALS AND METHODS This study was a retrospective multi-institutional trial from centers across the United States and Canada. Demographic, clinical, and outcomes data were collected. Bivariate and multivariable analyses were performed to determine the effects of region and microbiology on outcomes. RESULTS A total of 622 patients were included in this study. Polymicrobial infections (45%) were the most prevalent infections in all regions. On bivariate analysis, Clostridium and polymicrobial infections had higher mean Laboratory Risk Indicator for Necrotizing Fasciitis scores and American Association for the Surgery of Trauma grades (P
- Subjects :
- Adult
Male
medicine.medical_specialty
Polymicrobial infection
Canada
Demographics
Severity of Illness Index
03 medical and health sciences
0302 clinical medicine
Streptococcal Infections
Epidemiology
Prevalence
Medicine
Humans
Fasciitis, Necrotizing
Fasciitis
Societies, Medical
Aged
Retrospective Studies
business.industry
Coinfection
Soft Tissue Infections
Middle Aged
medicine.disease
Survival Analysis
United States
Surgery
Logistic Models
Multicenter study
Risk indicator
030220 oncology & carcinogenesis
Clostridium Infections
030211 gastroenterology & hepatology
Female
business
Regional differences
Subjects
Details
- ISSN :
- 10958673
- Volume :
- 243
- Database :
- OpenAIRE
- Journal :
- The Journal of surgical research
- Accession number :
- edsair.doi.dedup.....92025f313332aed43481812535166ade