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Elastography Method for Reconstruction of Nonlinear Breast Tissue Properties
- Source :
- International Journal of Biomedical Imaging, Vol 2009 (2009), International Journal of Biomedical Imaging
- Publication Year :
- 2009
- Publisher :
- Hindawi Limited, 2009.
-
Abstract
- Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex breast tissue properties. The elastic parameters are estimated by optimally minimizing the difference between the computed forces and experimental measures. A nonlinear adjoint method is derived to calculate the gradient of the objective function, which significantly enhances the numerical efficiency and stability. Simulations are conducted on a three-dimensional heterogeneous breast phantom extracting from real imaging including fatty tissue, glandular tissue, and tumors. An exponential-form of nonlinear material model is applied. The effect of noise is taken into account. Results demonstrate that the proposed nonlinear method opens the door toward nonlinear elastography and provides guidelines for future development and clinical application in breast cancer study.
- Subjects :
- lcsh:Medical physics. Medical radiology. Nuclear medicine
Pathology
medicine.medical_specialty
Breast tissue
lcsh:Medical technology
Article Subject
medicine.diagnostic_test
Computer science
Noise (signal processing)
Quantitative Biology::Tissues and Organs
lcsh:R895-920
Linear elasticity
Physics::Medical Physics
medicine.disease
Stability (probability)
Breast phantom
Nonlinear system
Breast cancer
lcsh:R855-855.5
medicine
Radiology, Nuclear Medicine and imaging
Elastography
Research Article
Biomedical engineering
Subjects
Details
- Language :
- English
- ISSN :
- 16874196 and 16874188
- Volume :
- 2009
- Database :
- OpenAIRE
- Journal :
- International Journal of Biomedical Imaging
- Accession number :
- edsair.doi.dedup.....91caebba02909d2a3e7be24dd7047999