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Neurogenesis of sensory neurons in the primate olfactory system after section of the fila olfactoria
- Source :
- Brain Research. 186:289-300
- Publication Year :
- 1980
- Publisher :
- Elsevier BV, 1980.
-
Abstract
- Axotomy of the olfactory sensory neurons in the adult primate squirrel monkey induces retrograde degeneration of the perikarya in the nasal neuroepithelium. The process of neuronal degeneration is rapid and by the 10th day the olfactory neuroepithelium is deprived of all mature neurons. Basal cells, supporting cells and the Bowman's glands are unaffected by the surgical procedure. The degeneration of the neurons is followed by intense mitotic activity of the basal cells of the neuroepithelium. At 30 days survival several young, mature neurons are present again in the neuroepithelium. At 60--90 survival days the neuroepithelium reacquires a population of neurons similar to controls. The persistence of neurogenesis and the replacement of experimentally degenerated neurons in an adult, non-human primate is briefly discussed.
- Subjects :
- Central Nervous System
Male
Olfactory system
Retrograde Degeneration
animal structures
medicine.medical_treatment
Central nervous system
Biology
Olfactory mucosa
Olfactory Mucosa
medicine
Animals
Saimiri
Molecular Biology
Neurons
General Neuroscience
Neurogenesis
Haplorhini
Olfactory Pathways
Olfactory Bulb
Olfactory bulb
Neuroepithelial cell
medicine.anatomical_structure
nervous system
Nerve Degeneration
embryonic structures
sense organs
Neurology (clinical)
Axotomy
Neuroscience
Developmental Biology
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 186
- Database :
- OpenAIRE
- Journal :
- Brain Research
- Accession number :
- edsair.doi.dedup.....91a4afdf3412e7fa6833d397c7acdc12