Back to Search
Start Over
Erythropoietin and Brain Magnetic Resonance Imaging Findings in Hypoxic-Ischemic Encephalopathy: Volume of Acute Brain Injury and 1-Year Neurodevelopmental Outcome
- Source :
- The Journal of pediatrics. 186
- Publication Year :
- 2016
-
Abstract
- In the Neonatal Erythropoietin and Therapeutic Hypothermia Outcomes study, 9/20 erythropoietin-treated vs 12/24 placebo-treated infants with hypoxic-ischemic encephalopathy had acute brain injury. Among infants with acute brain injury, the injury volume was lower in the erythropoietin than the placebo group (P = .004). Higher injury volume correlated with lower 12-month neurodevelopmental scores. Trial registration ClinicalTrials.gov : NCT01913340 .
- Subjects :
- Male
Time Factors
Encephalopathy
Neuroprotection
Hypoxic Ischemic Encephalopathy
03 medical and health sciences
0302 clinical medicine
Double-Blind Method
030225 pediatrics
medicine
Humans
Prospective Studies
Prospective cohort study
Erythropoietin
medicine.diagnostic_test
business.industry
Infant, Newborn
Infant
Magnetic resonance imaging
Hypothermia
medicine.disease
Magnetic Resonance Imaging
United States
Neuroprotective Agents
Treatment Outcome
Anesthesia
Brain Injuries
Pediatrics, Perinatology and Child Health
Hypoxia-Ischemia, Brain
Female
medicine.symptom
business
030217 neurology & neurosurgery
medicine.drug
Diffusion MRI
Subjects
Details
- ISSN :
- 10976833
- Volume :
- 186
- Database :
- OpenAIRE
- Journal :
- The Journal of pediatrics
- Accession number :
- edsair.doi.dedup.....918f4bfc53dffdd582d71d6e920470d6