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Pediatric brain tumor care in a Sub-Saharan setting: current poise of a precariously loaded dice

Authors :
Dubem S Amuta
E O Uche
Wilfred C Mezue
Christopher Bismarck Eke
Mats Ryttlefors
Obinna V. Ajuzieogu
Ephraim Onyia
Dung A Guga
N J Uche
Samuel Okpara
Okechukwu C Okafor
Magnus Tisell
Source :
British journal of neurosurgery. 35(2)
Publication Year :
2020

Abstract

To evaluate the current status of pediatric brain tumor (PBT) care and identify determinants and profiles of survival and school attendance.An 8-year institution-based prospective longitudinal study. All cases investigated with neuroimaging and treated were enrolled. Data was analyzed with SPSS (Inc) Chicago IL, USA version 23. Chi Square test, One-way ANOVA and confidence limits were used to evaluate associations at the 95% level of significance. Ethical approval for our study was obtained Health Research Ethics Committee of our hospital.Among 103 patients enrolled, 92 satisfied our study criteria. There were 45 males and 39 females, M: F = 0.8. The mean age was 9.5 ± 2.1 years 95%CI with a range of 7 months to 16 years. The most common symptom was headache for supratentorial lesions (73%) and gait disturbance (80.2%) for infratentorial lesions. More tumors were supratentorial in location 51 (55.4%), 35 (38.1%) were infratentorial and 6 (6.5%) were transtentorial. Craniopharyngiomas (Survival profile in this series suggests some improvement in comparison to previous studies from our region, Hemoglobin genotype profiles may signature paediatric brain tumor phenotypes in our setting.

Details

ISSN :
1360046X
Volume :
35
Issue :
2
Database :
OpenAIRE
Journal :
British journal of neurosurgery
Accession number :
edsair.doi.dedup.....91387b3d4913f39b2a928e3a285778ae