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Clinical impact of FDG PET/CT in alimentary tract malignancies: an updated review
- Source :
- Abdominal Radiology. 45:1018-1035
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- The use of 18F-fluorodeoxyglucose (FDG) positron emission tomography combined with computed tomography (PET/CT) is well established in the evaluation of alimentary tract malignancies. This review of the literature and demonstration of correlative images focuses on the current role of PET/CT in the diagnosis (including pathologic/clinical staging) and post-therapy follow-up of esophageal, gastric, and colorectal cancers. PET/CT provides utility in the management of esophageal cancer, including detection of distant disease prior to resection. In gastric cancer, PET/CT is useful in detecting solid organ metastases and in characterizing responders vs. non-responders after neoadjuvant chemotherapy, the latter of which have poorer overall survival. In patients with GIST tumors, PET/CT also determines response to imatinib therapy with greater expedience as compared to CECT. For colorectal cancer, PET/CT has proven helpful in detecting hepatic and other distant metastases, treatment response, and differentiating post-radiation changes from tumor recurrence. Our review also highlights several pitfalls in PET/CT interpretation of alimentary tract lesions.
- Subjects :
- medicine.medical_specialty
Colorectal cancer
Urology
Digestive System Neoplasms
Malignancy
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
Fluorodeoxyglucose F18
Positron Emission Tomography Computed Tomography
Internal medicine
medicine
Humans
Radiology, Nuclear Medicine and imaging
Neoplasm Staging
PET-CT
Radiological and Ultrasound Technology
GiST
medicine.diagnostic_test
business.industry
Gastroenterology
Cancer
Esophageal cancer
Hepatology
medicine.disease
Positron emission tomography
030220 oncology & carcinogenesis
Radiology
Radiopharmaceuticals
business
Subjects
Details
- ISSN :
- 23660058 and 2366004X
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- Abdominal Radiology
- Accession number :
- edsair.doi.dedup.....907e6c3bcf185a2bee375c150f0f061a