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Health-related quality of life of thyroid cancer patients undergoing radioiodine therapy: a cohort real-world study in a reference public cancer hospital in Brazil
- Source :
- Supportive Care in Cancer. 28:3771-3779
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- The purpose of this study was to access changes in health-related quality of life (HRQoL) caused by radioiodine therapy (RAI) in thyroid cancer patients. Prospective cohort study at Brazilian National Cancer Institute with patients enrolled between March 2015 and June 2017. RAI was performed by administration of 1.11 to 9.25 GBq of Na131I. EORTC QLQ-C30 v3 and EORTC QLQ-H&N35 questionnaires were applied to determine HRQoL at baseline, 1 week and 3 months after RAI. HRQoL during follow-up was evaluated by calculation of score absolute changes in each domain. Descriptive analysis was performed by measures of central tendency and dispersion. Changes in HRQoL were evaluated by paired t-test. The association between social demographic and clinical data and HRQoL was assessed by univariate linear regression for significantly changed domains, and p
- Subjects :
- Adult
Male
medicine.medical_specialty
Nausea
Cancer Care Facilities
Cohort Studies
Iodine Radioisotopes
03 medical and health sciences
0302 clinical medicine
Quality of life
Surveys and Questionnaires
Internal medicine
Humans
Medicine
Prospective Studies
Thyroid Neoplasms
030212 general & internal medicine
Prospective cohort study
Thyroid cancer
Aged
business.industry
Cancer
Radioiodine therapy
Middle Aged
medicine.disease
humanities
Oncology
030220 oncology & carcinogenesis
Cohort
Quality of Life
Vomiting
Female
medicine.symptom
business
Brazil
Subjects
Details
- ISSN :
- 14337339 and 09414355
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Supportive Care in Cancer
- Accession number :
- edsair.doi.dedup.....904f8eb071837c1e183651a63ded1848