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Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients
Cholesterol Levels Are Associated with 30-day Mortality from Ischemic Stroke in Dialysis Patients
- Source :
- Journal of Stroke and Cerebrovascular Diseases. 26:1349-1356
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- We investigated the impact of serum cholesterol levels on 30-day mortality after ischemic stroke in dialysis patients.From the Taiwan Stroke Registry data, we identified 46,770 ischemic stroke cases, including 1101 dialysis patients and 45,669 nondialysis patients from 2006 to 2013.Overall, the 30-day mortality was 1.46-fold greater in the dialysis group than in the nondialysis group (1.75 versus 1.20 per 1000 person-days). The mortality rates were 1.64, .62, 2.82, and 2.23 per 1000 person-days in dialysis patients with serum total cholesterol levels of 120 mg/dL, 120-159 mg/dL, 160-199 mg/dL, and ≥200 mg/dL, respectively. Compared to dialysis patients with serum total cholesterol levels of 120-159 mg/dL, the corresponding adjusted hazard ratios of mortality were 4.20 (95% confidence interval [CI] = 1.01-17.4), 8.06 (95% CI = 2.02-32.2), and 6.89 (95% CI = 1.59-29.8) for those with cholesterol levels of 120 mg/dL, 160-199 mg/dL, and ≥200 mg/dL, respectively.Dialysis patients with serum total cholesterol levels of ≥160 mg/dL or 120 mg/dL on admission are at an elevated hazard of 30-day mortality after ischemic stroke.
- Subjects :
- Male
Stroke registry
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Taiwan
Kaplan-Meier Estimate
030204 cardiovascular system & hematology
Dialysis patients
Brain Ischemia
03 medical and health sciences
chemistry.chemical_compound
Patient Admission
0302 clinical medicine
Renal Dialysis
Risk Factors
Internal medicine
medicine
Humans
Registries
Serum cholesterol
Dialysis
Aged
Proportional Hazards Models
Aged, 80 and over
Cholesterol
business.industry
Mortality rate
Rehabilitation
Middle Aged
Prognosis
Stroke
chemistry
30 day mortality
Ischemic stroke
Cardiology
Kidney Failure, Chronic
Female
Surgery
Neurology (clinical)
Cardiology and Cardiovascular Medicine
business
Biomarkers
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 10523057
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Journal of Stroke and Cerebrovascular Diseases
- Accession number :
- edsair.doi.dedup.....902504cf63b4eaee33697555d25ad49d
- Full Text :
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.02.007