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Prenatal diagnosis and long‐term follow‐up of a Chinese patient with mosaic variegated aneuploidy and its molecular analysis

Authors :
Ivan F M Lo
Anita Sik Yau Kan
Hei‐Yee Tse
Wai-Keung Tam
Kelvin Y.K. Chan
Wing Cheong Leung
Ho Ming Luk
Sheng Mou Lin
Mary Hoi Yin Tang
Source :
Clinical Case Reports, Vol 8, Iss 8, Pp 1369-1375 (2020), Clinical Case Reports
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

Mosaic variegated aneuploidy (MVA) is a rare genetic disorder caused by mutations in BUB1B, CEP57, or TRIP13. We describe the prenatal diagnosis, molecular characterization, and clinical management of a long‐lived patient with BUB1B‐related MVA.

Details

Language :
English
ISSN :
20500904
Volume :
8
Issue :
8
Database :
OpenAIRE
Journal :
Clinical Case Reports
Accession number :
edsair.doi.dedup.....901c647833b647e03182eef8ae970333