Back to Search
Start Over
Highly Aminated Mesoporous Silica Nanoparticles with Cubic Pore Structure
- Source :
- Journal of the American Chemical Society. 133:172-175
- Publication Year :
- 2010
- Publisher :
- American Chemical Society (ACS), 2010.
-
Abstract
- Mesoporous silica with cubic symmetry has attracted interest from researchers for some time. Here, we present the room temperature synthesis of mesoporous silica nanoparticles possessing cubic Pm3n symmetry with very high molar ratios (>50%) of 3-aminopropyl triethoxysilane. The synthesis is robust allowing, for example, co-condensation of organic dyes without loss of structure. By means of pore expander molecules, the pore size can be enlarged from 2.7 to 5 nm, while particle size decreases. Adding pore expander and co-condensing fluorescent dyes in the same synthesis reduces average particle size further down to 100 nm. After PEGylation, such fluorescent aminated mesoporous silica nanoparticles are spontaneously taken up by cells as demonstrated by fluorescence microscopy.
- Subjects :
- Molecular Structure
Surface Properties
Silicon dioxide
Nanoparticle
Nanotechnology
General Chemistry
Mesoporous silica
Silicon Dioxide
Biochemistry
Fluorescence
Article
Catalysis
chemistry.chemical_compound
Mesoporous organosilica
Colloid and Surface Chemistry
chemistry
Chemical engineering
Triethoxysilane
Nanoparticles
Particle size
Particle Size
Porosity
Amination
Subjects
Details
- ISSN :
- 15205126 and 00027863
- Volume :
- 133
- Database :
- OpenAIRE
- Journal :
- Journal of the American Chemical Society
- Accession number :
- edsair.doi.dedup.....90110588876811275aa7a9827f1ea394