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Genetic variation and association of insulin-like growth factor binding protein-3 with performance in Swine
- Source :
- Biochemical genetics. 47(3-4)
- Publication Year :
- 2008
-
Abstract
- Genetic variation of insulin-like growth factor binding protein-3 was analyzed in 17 pig breeds (14 native Chinese and 3 European). Using PCR-single strand conformation polymorphism, we found a polymorphism in intron 2, and this SNP was the combined mutation of G897T-G903A-C911T. The Chinese breeds carried a higher TAT/TAT genotype frequency (over 50%), except for Bamei (22%), Yujiang Black (0.0%), and Erhualian (10.0%); the European breeds had a higher GGC/GGC genotype frequency (Large White 1.67%, Landrace 13.89%, Duroc 0.0%). The allelic frequency of TAT in Chinese breeds was over 50%, except for Yujiang Black (12.5%); the allelic frequency of GGC was over 50% in all European breeds. The effect of genotype on 43 performance traits was investigated in one population (Lantang × Landrace). Pigs with the TAT/TAT genotype had higher B-point and C-point back-fat thickness than pigs with the GGC/GGC genotype. The TAT/TAT pigs also scored higher in meat color than the GGC/GGC pigs. These results implied that IGFBP-3 may affect meat quality and carcass traits.
- Subjects :
- Genotype
medicine.medical_treatment
Population
Sus scrofa
Biology
Breeding
Biochemistry
Insulin-like growth factor
Gene Frequency
Polymorphism (computer science)
Genetic variation
Genetics
medicine
SNP
Animals
Animal Husbandry
education
Molecular Biology
Allele frequency
Ecology, Evolution, Behavior and Systematics
Polymorphism, Single-Stranded Conformational
education.field_of_study
Base Sequence
General Medicine
Genotype frequency
Insulin-Like Growth Factor Binding Protein 3
Subjects
Details
- ISSN :
- 15734927
- Volume :
- 47
- Issue :
- 3-4
- Database :
- OpenAIRE
- Journal :
- Biochemical genetics
- Accession number :
- edsair.doi.dedup.....900739bf19ce0338c387baea85e9a763