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Potentialities of aptasensors in cancer diagnosis

Authors :
Avinash Sharma
Kanika Dulta
Kamal Dua
Dong-Soo Shin
Rupak Nagraik
Deepak Kumar
Dinesh Kumar Chellappan
Sachin Kumar Singh
Source :
Materials Letters. 308:131240
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Cancer is a potentially fatal disease that affects people worldwide. Cancer diagnosis at a later stage is a major challenge today, and will provide essential, faster and more accurate treatment using novel diagnostic techniques. Unfortunately, traditional methods of diagnosis have not been fully helpful and most cancers are diagnosed too late. Early-stage and sensitive diagnostics for various kinds of cancer can assist patients in gaining access to the best treatment options available to combat these diseases. Development of a quick, simple, portable, and low-cost method for detecting cancer diseases is critical. As a result, biosensors have become one of the most important study fields in recent years as a potentially beneficial tool for the identification and detection of a variety of cancer cells in the early stage. Aptasensors (aptamers-based biosensors) are one of several new detection approaches that have lately showed promise in terms of sensitivity, detection or identification, of all types of cancer cells. Aptasensors can detect small and very high-selectivity cancer markers, as well as optimized time and cost savings. In this report, we discussed the current issues of aptasensors in cancer diagnostics, as well its potential future prospects.

Details

ISSN :
0167577X
Volume :
308
Database :
OpenAIRE
Journal :
Materials Letters
Accession number :
edsair.doi.dedup.....8ff47f233a48d6d6bae313b9a27f9e97
Full Text :
https://doi.org/10.1016/j.matlet.2021.131240