Back to Search
Start Over
IMAGE QUALITY AND ARTIFACTS ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
- Source :
- Retina. 37:1660-1673
- Publication Year :
- 2017
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2017.
-
Abstract
- To study image quality and artifacts seen on optical coherence tomography angiography (OCTA).Sixty-five consecutive patients with unilateral posterior uveal melanoma treated with plaque radiotherapy had OCTA during follow-up. Optical coherence tomography angiography was performed on both the affected and fellow eye. Signal strength and frequency of image artifacts on en face images were compared between affected and fellow eyes.A total of 130 eyes in 65 patients were analyzed, the mean age at time of OCTA was 55 years (median: 56, range: 12-81 years), and 39 (39/65, 60%) were female. Majority of tumors were located in the choroid (62/65, 95%) and extramacular (55/65, 85%). The mean distance to the foveola was 4 mm (median: 3, range: 0-18 mm) and optic nerve was 4 mm (median: 4, range: 0-16 mm). Optical coherence tomography angiography was performed at a mean 46 months after plaque radiotherapy. Most patients had a history of radiation maculopathy or papillopathy in the treated eye at the time of OCTA (46/65, 71%). Overall, 95 eyes (95/130, 73%) had at least one significant artifact on OCTA. The most common major artifacts were loss of focus (71/130, 55%), broad (5 pixels width and4 lines) blink lines (48/130, 37%), motion artifact (34/130, 26%), specular dot (33/130, 25%), and edge duplication (10/130, 8%). Statistically, eyes treated with plaque radiotherapy (affected vs. fellow eye) were more likely to have at least one major OCTA artifact (92 vs. 54%, P0.001) and, specifically, loss of focus was more frequent (78 vs. 31%, P0.001). Multivariate analysis found decreased visual acuity significantly associated with higher incidence of broad blink lines (P = 0.0166) and loss of signal (P0.0001), whereas male sex was associated with increased loss of signal (P = 0.0015), and distance to the foveola was related to edge duplication (P = 0.0119).Image artifacts on OCTA are commonly encountered and appear to be more frequent in eyes with pathology and poor visual acuity. Recognition of these artifacts might help improve image interpretation and decision making.
- Subjects :
- Adult
Male
Uveal Neoplasms
0301 basic medicine
Choroidal melanoma
medicine.medical_specialty
Adolescent
genetic structures
Image quality
medicine.medical_treatment
Brachytherapy
Uveal Neoplasm
Young Adult
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Fluorescein Angiography
Child
Melanoma
Aged
Aged, 80 and over
medicine.diagnostic_test
Plaque radiotherapy
business.industry
Choroid Neoplasms
Optical Imaging
General Medicine
Optical coherence tomography angiography
Middle Aged
Fluorescein angiography
eye diseases
Ophthalmology
030104 developmental biology
Multivariate Analysis
030221 ophthalmology & optometry
Female
sense organs
Radiology
Tomography
Artifacts
business
Tomography, Optical Coherence
Subjects
Details
- ISSN :
- 0275004X
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Retina
- Accession number :
- edsair.doi.dedup.....8fd35d4f8cca613ea3e54c1b01a85059
- Full Text :
- https://doi.org/10.1097/iae.0000000000001414