Supplementary Data from RUNX1 Is a Driver of Renal Cell Carcinoma Correlating with Clinical Outcome

All Supplementary data figures and legends. Supplementary Figure 1. In Silico analysis of RUNX1 expression in human kidney cancer. Supplementary Figure 2. Knockdown of RUNX1 with shRNA causes a growth defect in two ccRCC cell lines. Supplementary Figure 3. RUNX1 deletion in 786-O* cells and orthotopic xenograft. Supplementary Figure 4. Principle component analysis. Gene expression variances between control (786-O pX, Red) and RUNX1 CRISPR cells (786-O A1, yellow and 786-O A3, purple). Supplementary Figure 5. Heterozygous deletion of RUNX2 in a GEM model of kidney cancer does not affect survival.