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The potential of banana fruit Ranggap (Musa paradisiaca var. Troglodytarum) as an excipient alternative to oral tablet dosage form
- Source :
- Pharmacy Education. 21:98-107
- Publication Year :
- 2021
- Publisher :
- International Pharmaceutical Federation (FIP), 2021.
-
Abstract
- Introduction: Starch is one of the ingredients that has many benefits, including in the pharmaceutical field, especially as a pharmaceutical excipient in pharmaceutical formulations. Aim: This study aims to isolate, characterise, and formulate the starch of banana fruit (Musa paradisiaca var. Troglodytarum) into tablet dosage forms. Methods: The characteristics of the perceived banana starch can be said to be comparable to that of corn starch so that it is expected to be used as a source of starch which can be used as a pharmaceutical excipient. The starch of isolated banana fruit was used as a filler, binder, and crusher in the wet granulation method tablet formulations with concentrations of 2%, 3%, and 5%. Results: The physicochemical characteristics of starch isolated from banana fruit are considered to meet the requirements of pharmaceutical excipients required in the Handbook of Pharmaceutical Excipients 6th edition and the United States Pharmacopeia 32nd edition. Conclusion: Of the total formulas tested, tablets with binder content of banana starch 3%, 5% and 10% corn starch meet the tablet evaluation requirements.
- Subjects :
- food.ingredient
Starch
Pharmaceutical Science
Excipient
Pharmacy
010501 environmental sciences
Musa × paradisiaca
01 natural sciences
Dosage form
Education
Granulation
chemistry.chemical_compound
food
medicine
Food science
040502 food science
0105 earth and related environmental sciences
Mathematics
Traditional medicine
Oral Tablet Dosage Form
biology
food and beverages
04 agricultural and veterinary sciences
biology.organism_classification
chemistry
0405 other agricultural sciences
Filler (animal food)
Corn starch
medicine.drug
Subjects
Details
- ISSN :
- 14772701 and 15602214
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Pharmacy Education
- Accession number :
- edsair.doi.dedup.....8f02f58b7734c9eb5b8abad4a7701c4b