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Photo-protection and controlled release of folic acid using edible alginate/chitosan nanolaminates

Authors :
Alejandra Acevedo-Fani
Robert Soliva-Fortuny
Olga Martín-Belloso
Source :
Repositorio Abierto de la UdL, Universitad de Lleida, Recercat: Dipósit de la Recerca de Catalunya, Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya), Recercat. Dipósit de la Recerca de Catalunya, instname
Publication Year :
2018
Publisher :
Elsevier BV, 2018.

Abstract

The formation, characterization, photo-protective properties and release profiles of folic acid-loaded nanolaminated films were investigated by UV-visible spectroscopy, FTIR, Raman and SEM microscopy. Food-grade alginate/chitosan nanolaminates were obtained by the layer-by-layer technique and folic acid (FA) was incorporated by post-diffusion. The FA concentration of loading solutions and immersion time significantly affected the FA content in nanolaminates. The maximum FA loading was reached using FA solutions at 10 mg/mL for 30 min (54.4 μg/cm2), or 12.5 mg/mL for 120 min (≈70 μg/cm2). Nanolaminates containing FA were more stable under ultraviolet light exposure than non-encapsulated FA. The rate and concentration of FA released from nanolaminates were greater at buffer pH 7 than at pH 3, which might play a key role in the delivery and bioavailability of nutraceuticals. These results provide important information for the design of nanolaminates containing hydrophilic active compounds for food applications. This research was supported by the Ministerio de Ciencia e Innovación throughout the projects AGL2009-11475 and MINECO ALG2012-35635. Author Acevedo-Fani also thanks to the University of Lleida for the pre-doctoral grant.

Details

ISSN :
02608774
Volume :
229
Database :
OpenAIRE
Journal :
Journal of Food Engineering
Accession number :
edsair.doi.dedup.....8ef3b7fc9fb0a841f52895404477bd47
Full Text :
https://doi.org/10.1016/j.jfoodeng.2017.03.024