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Komagataeibacter xylinus as a novel probiotic candidate with high glucose conversion rate properties
- Source :
- Heliyon, Heliyon, Vol 5, Iss 4, Pp e01571-(2019)
- Publication Year :
- 2019
- Publisher :
- Elsevier, 2019.
-
Abstract
- Promoting general health in terms of obesity and diabetes prevention is recommended by health care systems. The objectives of this study were to isolate an efficient glucose-converting Komagataeibacter xylinus to cellulose and to evaluate the safety of the selected strain as a new generation of probiotics in the fight against obesity. Of the 97 samples, 43 K xylinus strains were isolated and evaluated for their glucose conversion rate and 5 strains were examined for probiotic activities by in vitro assays. A strain with significant performance was fed to rats in order to determine its safety status in vivo. The results revealed that the strain K.X.1 had high level of glucose conversion rate and significant survival rate in acidic pH and bile salt. No adverse clinical signs and bacterial translocation to rats’ organs were observed. The results showed that the strain of K. xylinus K.X.1 has suitable probiotic properties.
- Subjects :
- 0301 basic medicine
Komagataeibacter xylinus
Bacterial translocation
Safety status
Microbiology
Article
Food technology
law.invention
Food science
03 medical and health sciences
Probiotic
chemistry.chemical_compound
0302 clinical medicine
law
Diabetes mellitus
medicine
Natural product chemistry
Cellulose
lcsh:Social sciences (General)
lcsh:Science (General)
Nutrition
Multidisciplinary
Strain (chemistry)
medicine.disease
030104 developmental biology
chemistry
High glucose
lcsh:H1-99
030217 neurology & neurosurgery
lcsh:Q1-390
Subjects
Details
- Language :
- English
- ISSN :
- 24058440
- Volume :
- 5
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Heliyon
- Accession number :
- edsair.doi.dedup.....8eef2f113b60494823b6426644c6793c