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Exposure to Total Hydrocarbons During Cleanup of the Deepwater Horizon Oil Spill and Risk of Heart Attack Across 5 Years of Follow-up
- Source :
- Am J Epidemiol
- Publication Year :
- 2019
- Publisher :
- Oxford University Press (OUP), 2019.
-
Abstract
- Exposure to total hydrocarbons (THC) and volatile organic compounds from air pollution is associated with risk of coronary heart disease. THC exposure from oil spills might be similarly associated, but no research has examined this. We assessed the relationship between THC exposure during the response and cleanup of the Deepwater Horizon oil spill (Gulf of Mexico) and heart attack risk among 24,375 oil spill workers enrolled in the Gulf Long-Term Follow-up Study. There were 312 first heart attacks (self-reported physician-diagnosed myocardial infarction, or fatal coronary heart disease) ascertained during the study period (2010–2016). THC exposures were estimated using a job-exposure matrix incorporating self-reported activities and personal air measurements. We used Cox proportional hazards regression to estimate hazard ratios, with inverse-probability weights to account for confounding and censoring. Maximum THC levels of ≥0.30 parts per million (ppm) were associated with heart attack risk, with a 1.8-fold risk for exposure of ≥3.00 ppm versus
- Subjects :
- Adult
Time Factors
Epidemiology
Original Contributions
Myocardial Infarction
Air pollution
Coronary Disease
medicine.disease_cause
Petroleum Pollution
Toxicology
Young Adult
03 medical and health sciences
0302 clinical medicine
Risk Factors
Occupational Exposure
medicine
Humans
030212 general & internal medicine
Myocardial infarction
Aged
Proportional Hazards Models
Gulf of Mexico
Hazard ratio
Age Factors
Absolute risk reduction
Middle Aged
medicine.disease
Hydrocarbons
Confidence interval
Socioeconomic Factors
030220 oncology & carcinogenesis
Deepwater horizon
Oil spill
Environmental science
Water Pollutants, Chemical
Follow-Up Studies
Subjects
Details
- ISSN :
- 14766256 and 00029262
- Volume :
- 188
- Database :
- OpenAIRE
- Journal :
- American Journal of Epidemiology
- Accession number :
- edsair.doi.dedup.....8ed0f3449bce0d70a15429017005d157