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Wilms tumour surveillance in at-risk children: Literature review and recommendations from the SIOP-Europe Host Genome Working Group and SIOP Renal Tumour Study Group
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Since previous consensus-based Wilms tumour (WT) surveillance guidelines were published, novel genes and syndromes associated with WT risk have been identified, and diagnostic molecular tests for previously known syndromes have improved. In view of this, the International Society of Pediatric Oncology (SIOP)-Europe Host Genome Working Group and SIOP Renal Tumour Study Group hereby present updated WT surveillance guidelines after an extensive literature review and international consensus meetings. These guidelines are for use by clinical geneticists, pediatricians, pediatric oncologists and radiologists involved in the care of children at risk of WT. Additionally, we emphasise the need to register all patients with a cancer predisposition syndrome in national or international databases, to enable the development of better tumour risk estimates and tumour surveillance programs in the future.
- Subjects :
- 0301 basic medicine
Cancer Research
Host genome
Pediatrics
medicine.medical_specialty
Wilms tumour
Overgrowth syndrome
Renal tumour
Wilms Tumor
Novel gene
03 medical and health sciences
0302 clinical medicine
Cancer predisposition syndrome
Pediatric oncology
Medicine
Humans
Nephroblastoma
Surveillance
business.industry
Cancer predisposition
Genomics
WT1
Europe
030104 developmental biology
Oncology
030220 oncology & carcinogenesis
business
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....8ed0c46155efbd511a36ad6dda6b2db2