The possible effect of hashish on leukocytes and plasma lipids

The possible fluctuation of leukocytes and plasma lipids, 30 – 60 min after smoking hashish, was studied. Total phospholipid content in both leukocytes and plasma was increased in a similar way to the total lipid content after smoking hashish. Differences in most of the phospholipid classes in leukocytes and plasma before and after smoking hashish were observed while the values in controls and chronic users of the drug before smoking hashish were found to be relatively close. Findings are discussed in relation to the pharmacological action of the drug on liver lipid metabolism.