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How Does Preexisting Hypertension Affect Patients with Intracerebral Hemorrhage?
- Source :
- Journal of Stroke and Cerebrovascular Diseases. 28:782-788
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Patients with intracerebral hemorrhage (ICH) frequently present with hypertension, but it is unclear if this is due to pre-existing hypertension (prHTN) or to the bleed itself or associated pain. We sought to assess the relationship between prHTN and admission systolic blood pressure (aBP) and bleed severity.We retrospectively assessed the relationship between prHTN and aBP and NIHSS in patients with ICH at 3 institutions.Of 251 patients, 170 (68%) had prHTN based on history of hypertension/antihypertensive use. Median aBP was significantly higher in those with prHTN (155 mm Hg (IQR 135-181) versus 139 mm Hg (IQR 124-158), P.001). Patients with left ventricular hypertrophy (LVH) on electrocardiogram (ECG) or transthoracic echocardiogram (TTE) had significantly higher aBP than those without LVH (median aBP 195 mm Hg (IQR 155-216) for patients with LVH on ECG versus 147 mm Hg (IQR 129-163) for patients with no LVH on ECG, P.001; median aBP 181 mm Hg (IQR 153-214) for patients with LVH on TTE versus 152 mm Hg (IQR 137-169) for patients with no LVH on TTE, P = .01). prHTN was associated with a higher median NIHSS (11 (IQR 3-20) for patients with history of hypertension/antihypertensive use versus 6 (IQR 1-14) for patients without this history (P = .02); 9 (IQR 3-19) versus 5 (IQR 2-13) for patients with/without LVH on ECG (P = .085); and 10 (IQR 5-18) versus 5 (IQR 1-13) for patients with/without LVH on TTE (P = .046).Patients with ICH who have prHTN have higher aBP and NIHSS, suggesting that prHTN may worsen reactive hypertension in the setting of ICH.
- Subjects :
- Male
medicine.medical_specialty
genetic structures
Blood Pressure
Affect (psychology)
Severity of Illness Index
Disability Evaluation
Electrocardiography
03 medical and health sciences
Patient Admission
0302 clinical medicine
Risk Factors
Internal medicine
medicine
Humans
In patient
Antihypertensive Agents
Aged
Cerebral Hemorrhage
Ohio
Retrospective Studies
Intracerebral hemorrhage
business.industry
Rehabilitation
Middle Aged
Bleed
Prognosis
medicine.disease
Blood pressure
Echocardiography
Hypertension
Cardiology
Female
Hypertrophy, Left Ventricular
New York City
Surgery
Neurology (clinical)
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 10523057
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Journal of Stroke and Cerebrovascular Diseases
- Accession number :
- edsair.doi.dedup.....8e9dd35479821de7b7cfc0aa705c8887