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Thrombohaemorrhagic complications in 101 cases of myeloproliferative disorders: Relationship to platelet number and function
- Source :
- European Journal of Cancer and Clinical Oncology. 19:1593-1599
- Publication Year :
- 1983
- Publisher :
- Elsevier BV, 1983.
-
Abstract
- A series of 101 consecutive patients with chronic myeloproliferative disorders including polycythaemia vera, chronic myelogenous leukaemia, idiopathic myelofibrosis and essential thrombocythaemia have been studied. The aim was to establish the incidence of thrombotic and haemorrhagic complications and the possible role played by platelet number and function. The total incidence of haemostatic complications was 21% and the platelet functional tests investigated (platelet aggregation, generation of malondialdehyde, endogenous serotonin, beta-thromboglobulin and platelet coagulant activity) were of little help for predicting these clinical complications.
- Subjects :
- Adult
Blood Platelets
Male
medicine.medical_specialty
Polycythaemia
Adolescent
Platelet Function Tests
Platelet aggregation
Hemorrhage
Gastroenterology
Myeloproliferative Disorders
hemic and lymphatic diseases
Internal medicine
medicine
Humans
Platelet
Chronic myelogenous leukaemia
Polycythemia Vera
Aged
Platelet Count
business.industry
Incidence (epidemiology)
Thrombosis
Middle Aged
medicine.disease
Chronic myeloproliferative disorders
Leukemia
Oncology
Leukemia, Myeloid
Primary Myelofibrosis
Immunology
Female
business
Thrombocythemia, Essential
Subjects
Details
- ISSN :
- 02775379
- Volume :
- 19
- Database :
- OpenAIRE
- Journal :
- European Journal of Cancer and Clinical Oncology
- Accession number :
- edsair.doi.dedup.....8e9330b4e2df0e48b609b85cdf72a2ce