Back to Search
Start Over
Impact of influenza syndrome and flu vaccine on survival of cancer patients during immunotherapy in the INVIDIa study
Impact of influenza syndrome and flu vaccine on survival of cancer patients during immunotherapy in the INVIDIa study
- Source :
- Immunotherapy. 12(2)
- Publication Year :
- 2020
-
Abstract
- Aim: INVIDIa was a retrospective, multicenter study, exploring the clinical efficacy of influenza vaccine in 300 cancer patients undergoing immunotherapy. Overall survival (OS) was immature at the initial report. Methods: We reported the final OS analysis from the original study population and within subgroups. Results: Both at the univariate and multivariate analysis, the occurrence of influenza syndrome (IS) was significantly related to better OS in the overall population (OR: 0.53 [95% CI: 0.32–0.88]; p = 0.01). In the lung cancer subgroup, receiving flu vaccine and/or developing IS was related to better OS (p = 0.04). Within elderly patients, the flu vaccine was the main variable for the relative OS advantage (p = 0.05). Conclusion: Receiving the flu vaccine and/or developing IS was related to better OS within the INVIDIa population.
- Subjects :
- 0301 basic medicine
Oncology
Male
medicine.medical_specialty
Multivariate analysis
Influenza vaccine
influenza syndrome
medicine.medical_treatment
overall survival
Immunology
Population
flu vaccine
immune checkpoint inhibitors
immunotherapy
influenza vaccination
03 medical and health sciences
0302 clinical medicine
Internal medicine
Neoplasms
Influenza, Human
medicine
Overall survival
Immunology and Allergy
Humans
Immunologic Factors
Lung cancer
education
Aged
Retrospective Studies
education.field_of_study
business.industry
Cancer
Immunotherapy
Syndrome
medicine.disease
Survival Analysis
030104 developmental biology
Italy
Influenza Vaccines
030220 oncology & carcinogenesis
Population study
Female
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 17507448
- Volume :
- 12
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Immunotherapy
- Accession number :
- edsair.doi.dedup.....8e78ce235c8031e901a78afd0e03c6c1