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Effect of legumes as part of a low glycemic index diet on glycemic control and cardiovascular risk factors in type 2 diabetes mellitus: a randomized controlled trial
- Source :
- Archives of internal medicine. 172(21)
- Publication Year :
- 2012
-
Abstract
- Legumes, including beans, chickpeas, and lentils, are among the lowest glycemic index (GI) foods and have been recommended in national diabetes mellitus (DM) guidelines. Yet, to our knowledge, they have never been used specifically to lower the GI of the diet. We have therefore undertaken a study of low-GI foods in type 2 DM with a focus on legumes in the intervention.A total of 121 participants with type 2 DM were randomized to either a low-GI legume diet that encouraged participants to increase legume intake by at least 1 cup per day, or to increase insoluble fiber by consumption of whole wheat products, for 3 months. The primary outcome was change in hemoglobin A1c (HbA1c) values with calculated coronary heart disease (CHD) risk score as a secondary outcome.The low-GI legume diet reduced HbA1c values by -0.5% (95% CI, -0.6% to -0.4%) and the high wheat fiber diet reduced HbA1c values by -0.3% (95% CI, -0.4% to -0.2%). The relative reduction in HbA1c values after the low-GI legume diet was greater than after the high wheat fiber diet by -0.2% (95% CI, -0.3% to -0.1%; P.001). The respective CHD risk reduction on the low-GI legume diet was -0.8% (95% CI, -1.4% to -0.3%; P = .003), largely owing to a greater relative reduction in systolic blood pressure on the low-GI legume diet compared with the high wheat fiber diet (-4.5 mm Hg; 95% CI, -7.0 to -2.1 mm Hg; P.001).Incorporation of legumes as part of a low-GI diet improved both glycemic control and reduced calculated CHD risk score in type 2 DM.
- Subjects :
- Blood Glucose
Dietary Fiber
Male
medicine.medical_specialty
030309 nutrition & dietetics
medicine.medical_treatment
030209 endocrinology & metabolism
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Risk Factors
Internal medicine
Diabetes mellitus
Diet, Diabetic
Internal Medicine
Medicine
Humans
Glycemic
2. Zero hunger
Glycated Hemoglobin
0303 health sciences
Framingham Risk Score
business.industry
Type 2 Diabetes Mellitus
Fabaceae
Middle Aged
medicine.disease
3. Good health
Endocrinology
Glycemic index
Hemoglobin A
Diabetic diet
Treatment Outcome
Diabetes Mellitus, Type 2
Cardiovascular Diseases
Glycemic Index
Female
business
Subjects
Details
- ISSN :
- 15383679
- Volume :
- 172
- Issue :
- 21
- Database :
- OpenAIRE
- Journal :
- Archives of internal medicine
- Accession number :
- edsair.doi.dedup.....8e6ddbd63e712f8d822d2016a69bf081