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Data Supplement from Downregulation of MHC-I Expression Is Prevalent but Reversible in Merkel Cell Carcinoma

Authors :
Paul Nghiem
Jürgen C. Becker
Michele A. Cleary
Mary L. Disis
James S. Hardwick
Shigetoshi Sano
Hideki Nakajima
Shailender Bhatia
Margaret Madeleine
David M. Koelle
Aaron Seo
William T. Simonson
Kotaro Nagase
Renee Thibodeau
Shinichi Koba
David Schrama
Olga K. Afanasiev
Jayasri G. Iyer
Christoph Willmes
Andrew Tegeder
Kelly G. Paulson
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Allred proportion (ranging from 0-5) and intensity (ranging from 0-3) scores for each tumor. The median score among triplicate TMA cores and reviewers was utilized. Most MCC tumors with an Allred score of 7 continued to express MHC class I in all tumor cells, however the intensity of expression was significantly reduced as compared to those with an Allred score of 8.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....8e21b37ae9a8a91c6b8254cd93dad3a6
Full Text :
https://doi.org/10.1158/2326-6066.22536656