Back to Search
Start Over
Smell-induced gamma oscillations in human olfactory cortex are required for accurate perception of odor identity
- Source :
- PLoS Biology, PLoS Biology, Vol 20, Iss 1, p e3001509 (2022)
- Publication Year :
- 2022
- Publisher :
- Public Library of Science, 2022.
-
Abstract
- Studies of neuronal oscillations have contributed substantial insight into the mechanisms of visual, auditory, and somatosensory perception. However, progress in such research in the human olfactory system has lagged behind. As a result, the electrophysiological properties of the human olfactory system are poorly understood, and, in particular, whether stimulus-driven high-frequency oscillations play a role in odor processing is unknown. Here, we used direct intracranial recordings from human piriform cortex during an odor identification task to show that 3 key oscillatory rhythms are an integral part of the human olfactory cortical response to smell: Odor induces theta, beta, and gamma rhythms in human piriform cortex. We further show that these rhythms have distinct relationships with perceptual behavior. Odor-elicited gamma oscillations occur only during trials in which the odor is accurately perceived, and features of gamma oscillations predict odor identification accuracy, suggesting that they are critical for odor identity perception in humans. We also found that the amplitude of high-frequency oscillations is organized by the phase of low-frequency signals shortly following sniff onset, only when odor is present. Our findings reinforce previous work on theta oscillations, suggest that gamma oscillations in human piriform cortex are important for perception of odor identity, and constitute a robust identification of the characteristic electrophysiological response to smell in the human brain. Future work will determine whether the distinct oscillations we identified reflect distinct perceptual features of odor stimuli.<br />Intracranial recordings from human olfactory cortex reveal a characteristic spectrotemporal response to odors, including theta, beta and gamma oscillations, and show that high-frequency responses are critical for accurate perception of odors.
- Subjects :
- Olfactory system
Physiology
Sensory Physiology
Social Sciences
Piriform Cortex
Spectrum Analysis Techniques
Piriform cortex
Medicine and Health Sciences
Psychology
Biology (General)
Mammals
Chemistry
General Neuroscience
musculoskeletal, neural, and ocular physiology
Respiration
Brain
Eukaryota
Human brain
Sensory Systems
Signal Filtering
Smell
medicine.anatomical_structure
Inhalation
Vertebrates
Physical Sciences
Engineering and Technology
Sensory Perception
Anatomy
Cues
General Agricultural and Biological Sciences
psychological phenomena and processes
Research Article
Oscillatory response
QH301-705.5
Permutation
Research and Analysis Methods
Rodents
General Biochemistry, Genetics and Molecular Biology
Gamma Spectrometry
Rhythm
medicine
Animals
Humans
Beta (finance)
Olfactory System
Epilepsy
General Immunology and Microbiology
Discrete Mathematics
Organisms
Cognitive Psychology
Biology and Life Sciences
Olfactory Perception
Brain Waves
Odor
Combinatorics
Amniotes
Signal Processing
Odorants
Cognitive Science
Perception
Electrocorticography
Physiological Processes
Somatosensory perception
Neuroscience
Zoology
Mathematics
Subjects
Details
- Language :
- English
- ISSN :
- 15457885 and 15449173
- Volume :
- 20
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- PLoS Biology
- Accession number :
- edsair.doi.dedup.....8dfcd56176a31937d46836f8879ffb51