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Association of subjective health and abnormal cervical cytology in Japanese pregnant women: An adjunct study of the Japan Environment and Children's Study

Authors :
Kiyoshi Ito
Michihiro Satoh
Junichi Sugawara
Kosuke Tanaka
Hirohito Metoki
Zen Watanabe
Kaou Tanoue
Takahisa Murakami
Masatoshi Saito
Nobuo Yaegashi
Satoshi Okamoto
Noriyuki Iwama
Satomi Sasaki
Source :
Preventive Medicine Reports, Preventive Medicine Reports, Vol 24, Iss, Pp 101525-(2021)
Publication Year :
2021

Abstract

Highlights • Examined the association between abnormal cervical cytology and subjective health in pregnant women. • This study was an adjunct study of the Japan Environment and Children’s Study (JECS). • High subjective health was associated with high cervical cytology abnormality risk. • Young women may be at risk for cervical cancer even if they are aware of their health. • We should encourage young women who think they are healthy to get screened for cancer.<br />This study examines the association between abnormal cervical cytology and subjective health in pregnant women, as an adjunct to the Japan Environment and Children's Study, which cross-sectionally analyzed a subset of the prospective cohort. A total of 3024 pregnant women at a childbirth facility whose medical records of cervical cytology in the first trimester of pregnancy were transcribed and who responded to the subjective health questionnaire were included herein. They were classified into excellent, good, fair, and poor groups based on their subjective health. Cervical cytology results obtained from perinatal medical records were classified into normal and abnormal cytology based on the Bethesda classification. Logistic regression analysis adjusted for baseline characteristics, including age, pre-pregnancy body mass index, parity, and other possible confounding factors, was used. Of 3024 pregnant women, 106 (3.5%) had abnormal cytology, with the prevalence being 1.3%, 3.7%, 3.9%, and 4.0%, respectively (p = 0.055) in the poor, fair, good, and excellent groups. The baseline characteristics, namely age, history of gynecological diseases, Kessler 6-item psychological distress scale score, and history of mental illness, were significantly different between groups. Compared to the poor group, the other three groups had a significantly higher abnormal cytology risk after adjusting for confounding factors (Fair: adjusted OR [aOR] = 3.6, 95% CI [1.0–12.1]; Good: aOR = 4.6 [1.3–15.5]; Excellent: aOR = 4.6 [1.2–17.8]). This study encourages young women to undergo cervical cancer screening because they are at risk for cervical cancer even if they think that they are healthy, and preventive activities like regular screening are essential.

Details

Language :
English
ISSN :
22113355
Volume :
24
Database :
OpenAIRE
Journal :
Preventive Medicine Reports
Accession number :
edsair.doi.dedup.....8dbc624a34a1b29dab18657bc8e0f3a8