Single Nucleotide Polymorphisms in the IS 900 Sequence of Mycobacterium avium subsp. paratuberculosis Are Strain Type Specific

Insertion sequence IS 900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS 900 . This study, which analyzed the IS 900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.