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Significance of Apelin-13 for Inflammation and Cardiac Morphology in Peritoneal Dialysis Patients
- Source :
- Turkish Nephrology Dialysis Transplantation.
- Publication Year :
- 2018
- Publisher :
- AVES Publishing Co., 2018.
-
Abstract
- OBJECTIVE: Apelin-13 is a biomarker that was shown to be related to cardiovascular disease risk in peritoneal dialysis patients. The aim of our study was to investigate the association of serum apelin-13 levels with inflammation, carotid artery intima media thickness (CIMT) and echocardiographic parameters in peritoneal dialysis patients. MATERIAL and METHODS: 33 patient receiving peritoneal dialysis treatment (15 female) and 27 healthy controls (11 female) were enrolled. CIMT and echocardiographic measurements of all patients and controls were taken. Serum apelin-13 levels were measured by ELISA. Apelin-13, c-reactive protein (CRP), neutrophil-To-lymphocyte ratio (NLR), echocardiographic parameters and CIMT values were compared between patients and controls. RESULTS: Apelin-13 was lower in the patient group [58 (12-131) ng/L] than in the control group [76 (18-130) ng/L] (p=0.083). CRP, NLR, CIMT were significantly higher in patients than controls (p
- Subjects :
- Inflammation
Pathology
medicine.medical_specialty
Karotis Arter İntima-Media Kalınlığı
business.industry
Urology
medicine.medical_treatment
İnflamasyon
Carotid Intima-Media Thickness
Peritoneal dialysis
Apelin
medicine
Apelin-13
Surgery
medicine.symptom
business
Peritoneal Dialysis
Periton Diyalizi
Subjects
Details
- ISSN :
- 13007718
- Database :
- OpenAIRE
- Journal :
- Turkish Nephrology Dialysis Transplantation
- Accession number :
- edsair.doi.dedup.....8c5f7342cba3628a1e4094f7bd124648