Back to Search
Start Over
Response to letter regarding article, 'optimal duration of dual antiplatelet therapy after drug-eluting stent implantation: a randomized, controlled trial'
- Source :
- Circulation. 130(18)
- Publication Year :
- 2014
-
Abstract
- We thank Dr Sardar and colleagues for their interest in our recent article1 and appreciate the opportunity to reply. We agree that medication adherence is associated with clinical outcomes and remains an important issue in clinical drug trials. Unfortunately, there are no definite methods for assessing adherence to medications. In our study, pill count was used to determine medication adherence, and pharmacy data were electronically checked by medical insurance system. Medical adherence in this type of study is considered generally poor. Even in the Platelet Inhibition and Patient Outcome (PLATO) trial, medical adherence was ≈80%.2 In this context, we believe that medical adherence in our study seems to be acceptable. Time from index procedure to randomization was rather variable, but most patients were enrolled between 12 …
- Subjects :
- Male
medicine.medical_specialty
Randomization
Ticlopidine
medicine.medical_treatment
Alternative medicine
Pharmacy
Context (language use)
Coronary Artery Disease
law.invention
Randomized controlled trial
law
Physiology (medical)
medicine
Humans
Angioplasty, Balloon, Coronary
Intensive care medicine
Pill count
Aspirin
business.industry
Drug-Eluting Stents
Medical insurance
Drug-eluting stent
Physical therapy
Female
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15244539
- Volume :
- 130
- Issue :
- 18
- Database :
- OpenAIRE
- Journal :
- Circulation
- Accession number :
- edsair.doi.dedup.....8c5adc8453f6987304f0cb81d603fbd3