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Questionable long-term benefit of initial temozolomide monotherapy in IDH-mutant astrocytomas grade 2 and 3

Authors :
Weller, J
Katzendobler, S
Quach, S
Becker, H
Thiele, F
Dorostkar, M
Suchorska, B
Thon, N
Tonn, JC
Source :
73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV132 /20220525/
Publication Year :
2022
Publisher :
German Medical Science GMS Publishing House, 2022.

Abstract

Objective: The role of temozolomide monotherapy in IDH-mutant (IDHmut) astrocytomas after biopsy or tumor resection has not been conclusively determined. Methods: In this retrospective, single-center study, 151 patients with IDHmut WHO grade 2 or 3 according to WHO 2016 and seen between 2001 [for full text, please go to the a.m. URL]

Subjects

Subjects :
ddc: 610
Medicine and health

Details

Language :
English
Database :
OpenAIRE
Journal :
73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCV132 /20220525/
Accession number :
edsair.doi.dedup.....8c2b85d377edc0d8fb00e9e722adb3c6
Full Text :
https://doi.org/10.3205/22dgnc132