Comparison of hematological parameters of Brucella-seronegative naturally infected cattle with BVDV, BHV-1, and BHV-4

sozdutmaz, ibrahim/0000-0002-3712-7991; GAZYAGCI, SERKAL/0000-0002-0043-6942 WOS: 000368558800003 Abortion, neonatal deaths, and infertility cause important production losses in the livestock industry. Many viral infections are responsible for changes in hematological values of animals. This study aimed to find whether there is any difference in blood parameters of cattle that are naturally infected with BVDV, BHV-1, and BHV-4 and Brucella-seronegative. For this purpose, 401 whole-blood samples collected from cattle were analyzed by ELISA and PCR/RT-PCR to detect specific antibodies and antigens for BVDV, BHV-1, and BHV-4. Hematological analysis and results were compared between naturally infected BVDV, BHV-1, and BHV-4 groups and a control group. Results showed a statistically significant increase in hematological values of group 2 with BVDV compared to the corresponding parameters of group 1 (control) for mean corpuscular volume (MCV), hematocrit (Hct%), mean corpuscular hemoglobin concentration (MCHC), and mean platelet volume (MPV). The same was seen for hematological values of BHV-1 for MCV, Hct (%), and MPV and of BHV-4 for MPV (P < 0.005). However, it was determined that statistical differences in hematological values of naturally infected animals cannot be used as markers for clinical diagnosis of viral infections. Thus, we suggest that evaluations of hematological parameters with specific diagnostic tests are necessary to obtain more reliable results for the diagnosis of viral diseases. Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK-111O871]; KUBAP [2011/35] This study was summarized from a part of the dissertation of ME Aslan and was supported by the Scientific and Technological Research Council of Turkey (TUBITAK-111O871) and KUBAP (2011/35).