Supplementary Figure 1 from Cyclin E2 Overexpression Is Associated with Endocrine Resistance but not Insensitivity to CDK2 Inhibition in Human Breast Cancer Cells

PDF file, 929KB, Supplementary Figure 1: Cyclin E2 association with breast cancer subtype, grade, and outcome. A: Relationship between a second cyclin E2 probeset and breast cancer subtype, or histological grade. Box: upper and lower quartiles; dividing line: median. B: Relative expression of cyclin E1 and a second cyclin E2 probeset in individual tumours in breast cancer subtypes. C: Kaplan-Meier survival analysis of distant metastasis-free survival from ER-positive patients treated with endocrine therapy (n=287) and untreated ER-negative patients (n=106), using a 70% cutoff between high and low expression.