Myopia, corneal endothelial cell density and morphology in a Japanese population-based cross-sectional study: the JPHC-NEXT Eye Study

Authors :: Kazuo Tsubota
Kazumasa Yamagishi
Kenya Yuki
Naohiko Aketa
Hiroyasu Iso
Motoko Kawashima
Miki Uchino
Mariko Sasaki
Yoko Ozawa
Yuichi Uchino
Norie Sawada
Shoichiro Tsugane
Source :: Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021), Scientific Reports
Publication Year :: 2021
Publisher :: Nature Portfolio, 2021.
Abstract: This population-based cross-sectional study was performed to determine the mean corneal endothelial cell density (ECD), coefficient of variation (CV), and hexagonality (HEX), and their associations with myopia in Japanese adults living in Chikusei city. Of 7109 participants with available data, 5713 (2331 male and 3382 female) participants were eligible for analysis. After assessing the relationship between participant characteristics and spherical equivalent refraction (SER), the association of SER with the abnormal value of ECD (

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