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Resting-State Functional Magnetic Resonance Imaging for Brain Tumor Surgical Planning: Feasibility in Clinical Setting

Authors :
Giuseppe Mamone
Giovanni Grasso
Gianvincenzo Sparacia
Giuseppe Parla
Alessandro Perri
Roberto Miraglia
Roberto Cannella
Fabio Torregrossa
Vincenzina Lo Re
Sparacia, G.
Parla, G.
Cannella, R.
Perri, A.
Lo Re, V.
Mamone, G.
Miraglia, R.
Torregrossa, F.
Grasso, G.
Source :
World neurosurgery. 131
Publication Year :
2019

Abstract

The aim of this study was to introduce resting-state functional magnetic resonance imaging (rest-fMRI) capability for brain tumor surgical planning. rest-fMRI is an emerging functional neuroimaging technique potentially able to provide new insights into brain physiology and to provide useful information regarding brain tumors in preoperative and postoperative settings. rest-fMRI evaluates low-frequency fluctuations in the blood oxygen level–dependent signal while the subject is at rest during magnetic resonance imaging examination. Multiple resting-state networks have been identified, including the somatosensory, language, and visual networks, which are of primary importance for surgical planning. We discuss the feasibility of rest-fMRI examination before and after surgical resection of brain tumors in routine clinical practice and the usefulness of the information obtained for surgical planning in brain tumor resection. rest-fMRI is particularly useful for patients who are unable to cooperate with the task-based paradigm, such as children or patients who are sedated, paretic, or aphasic. Although standardization and validation of rest-fMRI are still ongoing, this technique is feasible and valuable and can be implemented for routine clinical surgical planning. © 2019 Elsevier Inc.

Details

ISSN :
18788769
Volume :
131
Database :
OpenAIRE
Journal :
World neurosurgery
Accession number :
edsair.doi.dedup.....8b5961f059df7c59bfee0b9ddb70a537