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Functional capacity, pulmonary function, and quality of life in hematopoietic stem cell transplantation survivors
- Source :
- Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 29(7)
- Publication Year :
- 2020
-
Abstract
- Hematopoietic stem cell transplantation (HSCT) is used as a treatment for several diseases. The objective was to evaluate the functional capacity, pulmonary function, and quality of life (QoL) in HSCT survivors. The patients were submitted to spirometry and six-minute walk test (6MWT) and evaluation of QoL (Functional Assessment of Cancer Therapy Bone Marrow Transplantation—FACT-BMT) and the level of physical activity (Human Activity Profile—HAP) in the post-HSCT outpatient ambulatory. The sample was composed of 103 individuals with a mean age of 42.1 ± 12 and a median HSCT time of 5 (2–11) years. The average distance walked in the 6MWT was 524.7 ± 73.5 m; the FACT-BMT score, 82 ± 8.7 points; FEV1, 76.8 ± 22.6%; and HAP, 71.9 ± 11.2 points. There was a significant difference between debilitated and physically active individuals for the variables: forced expiratory volume in the first second (FEV1) in liters (p = 0.008) and % of predicted (p = 0.017), FEV1/FVC (p = 0.032), distance on the 6MWT (p < 0.001), fatigue after the 6MWT (p < 0.001), and physical well-being (p = 0.005). HSCT survivors have long-term changes in functional capacity, pulmonary function, and QoL. Subjects more active had better results in pulmonary function and functional capacity.
- Subjects :
- Spirometry
Adult
Male
medicine.medical_specialty
medicine.medical_treatment
Cancer therapy
Hematopoietic stem cell transplantation
Pulmonary function testing
03 medical and health sciences
FEV1/FVC ratio
0302 clinical medicine
Quality of life
Internal medicine
medicine
Humans
030212 general & internal medicine
Survivors
Exercise
Lung
Fatigue
medicine.diagnostic_test
business.industry
Hematopoietic Stem Cell Transplantation
Middle Aged
Respiratory Function Tests
surgical procedures, operative
medicine.anatomical_structure
Functional Status
Oncology
030220 oncology & carcinogenesis
Ambulatory
Quality of Life
Respiratory Physiological Phenomena
Bone marrow
business
Subjects
Details
- ISSN :
- 14337339
- Volume :
- 29
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
- Accession number :
- edsair.doi.dedup.....8b50cb500260174967907442bec96783