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Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients

Authors :
Gaëtan Deslée
Jeanne-Marie Perotin-Collard
Ana Diaz Cives
Eric Bertin
J. Nardi
François Lebargy
C. Launois
Louis Boissière
Coralie Barbe
Sandra Dury
Isabelle Gaubil
Centre Hospitalier Universitaire de Reims (CHU Reims)
Plasticité de l'épithélium respiratoire dans les conditions normales et pathologiques - UMR-S 903 (PERPMP)
SFR CAP Santé (Champagne-Ardenne Picardie Santé)
Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Centre Hospitalier Universitaire de Reims (CHU Reims)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Reims Champagne-Ardenne (URCA)
Immunité Adaptative et Fonctionnalité des Barrières Biologiques - EA 4683 (IMAB)
Université de Reims Champagne-Ardenne (URCA)-SFR CAP Santé (Champagne-Ardenne Picardie Santé)
Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)
dormoy, valerian
Université de Reims Champagne-Ardenne (URCA)-Centre Hospitalier Universitaire de Reims (CHU Reims)-Institut National de la Santé et de la Recherche Médicale (INSERM)-SFR CAP Santé (Champagne-Ardenne Picardie Santé)
Source :
PLoS ONE, PLoS ONE, Public Library of Science, 2017, 12 (9), pp.e0185058. ⟨10.1371/journal.pone.0185058⟩, PLoS ONE, 2017, 12 (9), pp.e0185058. ⟨10.1371/journal.pone.0185058⟩, PLoS ONE, Vol 12, Iss 9, p e0185058 (2017)
Publication Year :
2017

Abstract

Objectives To assess the effects of bariatric surgery in patients with obesity on dyspnea and to analyze the relationships between improvement of dyspnea after bariatric surgery and changes in pulmonary function, especially Expiratory Reserve Volume (ERV) which is the lung volume abnormality most frequently associated with obesity. Methods Forty-five patients (5 males/40 females, mean Body Mass Index = 46.2 ± 6.8 kg/m2) were evaluated before and 6 to 12 months after bariatric surgery. Dyspnea was assessed by the modified Medical Research Council (mMRC) scale. Pulmonary function tests, arterial blood gases and six-minute walk test were performed. Laboratory parameters including C-Reactive Protein (CRP) were analyzed. Results Ninety percent of patients were dyspneic before surgery (mMRC scale ≥ 1) versus 59% after surgery (p

Details

ISSN :
19326203
Volume :
12
Issue :
9
Database :
OpenAIRE
Journal :
PloS one
Accession number :
edsair.doi.dedup.....8b2858ab950b5488903e08313a6a126f
Full Text :
https://doi.org/10.1371/journal.pone.0185058⟩