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Towards accurate and precise T 1 and extracellular volume mapping in the myocardium: a guide to current pitfalls and their solutions
- Source :
- Magma (New York, N.y.)
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- Mapping of the longitudinal relaxation time (T1) and extracellular volume (ECV) offers a means of identifying pathological changes in myocardial tissue, including diffuse changes that may be invisible to existing T1-weighted methods. This technique has recently shown strong clinical utility for pathologies such as Anderson- Fabry disease and amyloidosis and has generated clinical interest as a possible means of detecting small changes in diffuse fibrosis; however, scatter in T1 and ECV estimates offers challenges for detecting these changes, and bias limits comparisons between sites and vendors. There are several technical and physiological pitfalls that influence the accuracy (bias) and precision (repeatability) of T1 and ECV mapping methods. The goal of this review is to describe the most significant of these, and detail current solutions, in order to aid scientists and clinicians to maximise the utility of T1 mapping in their clinical or research setting. A detailed summary of technical and physiological factors, issues relating to contrast agents, and specific disease-related issues is provided, along with some considerations on the future directions of the field. Towards accurate and precise T1 and extracellular volume mapping in the myocardium: a guide to current pitfalls and their solutions. Available from: https://www.researchgate.net/publication/317548806_Towards_accurate_and_precise_T1_and_extracellular_volume_mapping_in_the_myocardium_a_guide_to_current_pitfalls_and_their_solutions [accessed Jun 13, 2017].
- Subjects :
- Male
Pathology
medicine.medical_specialty
Heart Diseases
Biophysics
Contrast Media
Gadolinium
Review Article
Signal-To-Noise Ratio
030204 cardiovascular system & hematology
computer.software_genre
030218 nuclear medicine & medical imaging
Breath Holding
Motion
03 medical and health sciences
0302 clinical medicine
Coronary Circulation
MD Multidisciplinary
Image Interpretation, Computer-Assisted
medicine
Humans
Radiology, Nuclear Medicine and imaging
Accuracy
Longitudinal Relaxation Time
Radiological and Ultrasound Technology
Myocardial tissue
business.industry
Myocardium
Heart
T1 mapping
Precision
Fibrosis
Magnetic Resonance Imaging
T 1 mapping
Nuclear Medicine & Medical Imaging
Cardiac Imaging Techniques
Diffuse fibrosis
Cardiovascular magnetic resonance
Female
Data mining
Extracellular Space
business
Research setting
computer
Extracellular volume
Subjects
Details
- ISSN :
- 13528661, 09685243, and 31754880
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Magnetic Resonance Materials in Physics, Biology and Medicine
- Accession number :
- edsair.doi.dedup.....8b222005e2f83bfffb88142510dedb6e