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Arrhythmic Mitral Valve Prolapse: Introducing an Era of Multimodality Imaging-Based Diagnosis and Risk Stratification
- Source :
- Diagnostics, Vol 11, Iss 467, p 467 (2021), Diagnostics, Repisalud, Instituto de Salud Carlos III (ISCIII)
- Publication Year :
- 2021
- Publisher :
- Multidisciplinary Digital Publishing Institute (MDPI), 2021.
-
Abstract
- Mitral valve prolapse is a common cardiac condition, with an estimated prevalence between 1% and 3%. Most patients have a benign course, but ever since its initial description mitral valve prolapse has been associated to sudden cardiac death. Although the causal relationship between mitral valve prolapse and sudden cardiac death has never been clearly demonstrated, different factors have been implicated in arrhythmogenesis in patients with mitral valve prolapse. In this work, we offer a comprehensive overview of the etiology and the genetic background, epidemiology, pathophysiology, and we focus on the state-of-the-art imaging-based diagnosis of mitral valve prolapse. Going beyond the classical, well-described clinical factors, such as young age, female gender and auscultatory findings, we investigate multimodality imaging features, such as alterations of anatomy and function of the mitral valve and its leaflets, the structural and contractile anomalies of the myocardium, all of which have been associated to sudden cardiac death. This research received no external funding Sí
- Subjects :
- medicine.medical_specialty
Clinical Biochemistry
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Review
030204 cardiovascular system & hematology
arrhythmia
cardiovascular magnetic resonance
echocardiography
mitral valve prolapse
multimodality imaging
risk factors
sudden cardiac death
Sudden cardiac death
03 medical and health sciences
0302 clinical medicine
Mitral valve
Internal medicine
Epidemiology
medicine
Mitral valve prolapse
In patient
030212 general & internal medicine
cardiovascular diseases
lcsh:R5-920
business.industry
medicine.disease
Young age
medicine.anatomical_structure
Risk stratification
Etiology
Cardiology
cardiovascular system
Risk factor
business
lcsh:Medicine (General)
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Diagnostics, Vol 11, Iss 467, p 467 (2021), Diagnostics, Repisalud, Instituto de Salud Carlos III (ISCIII)
- Accession number :
- edsair.doi.dedup.....8b1ca2eb939619138910064c727bf204