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Role of Eosinophil Relative Count and Neutrophil-to-Lymphocyte Ratio in the Assessment of Severity of Atopic Dermatitis
- Source :
- Acta Dermato-Venereologica, Vol 101, Iss 7, p adv00491 (2021)
- Publication Year :
- 2021
-
Abstract
- The aim of this study is to elucidate the relationship between 2 different types of severity-indicating parameters (i.e. between subjective and objective severity-indicating parametersin patients with atopic dermatitis. The disease severity of 55 patients with atopic dermatitis was assessed using 7 subjective parameters indicating severity, including visual analogue scale for itch, Patient-Oriented Eczema Measure, 5-D itch scale, Dermatology Life Quality Index, Eczema Area and Severity Index, body surface area, and Investigator Global Assessment, and 8 objective parameters indicating severity, including eosinophil relative count, neutrophil-to-lymphocyte ratio, lactate dehydrogenase, and thymus and activation-regulated chemokine. Five subjective parameters reflecting itch correlated significantly with eosinophil relative count, but not with neutrophil-to-lymphocyte ratio. In contrast, 2 subjective parameters, mainly reflecting the degree of inflammation and area of affected regions, correlated significantly with neutrophil-to-lymphocyte ratio. The eosinophil relative count may correlate with the degree of itch, while the neutrophil-to-lymphocyte ratio may correlate with the degree of inflammation and the area of the affected region. The eosinophil relative count and neutrophil-to-lymphocyte ratio may thus be stand-alone parameters from each other in the assessment of the severity of atopic dermatitis.
- Subjects :
- Visual analogue scale
Neutrophils
Eczema
Inflammation
macromolecular substances
Dermatology
Eczema Area and Severity Index
Severity of Illness Index
Dermatitis, Atopic
neutrophil-to-lymphocyte ratio
Medicine
Humans
objective parameters
itch
Lymphocytes
Neutrophil to lymphocyte ratio
subjective parameters
Body surface area
atopic dermatitis
business.industry
eosinophil relative count
General Medicine
Dermatology Life Quality Index
Atopic dermatitis
Eosinophil
medicine.disease
Eosinophils
medicine.anatomical_structure
RL1-803
Immunology
medicine.symptom
business
Subjects
Details
- ISSN :
- 16512057
- Volume :
- 101
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- Acta dermato-venereologica
- Accession number :
- edsair.doi.dedup.....8b181703eb35ef71455cf2e94cc00552