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Echocardiography in inflammatory heart disease: A comparison of giant cell myocarditis, cardiac sarcoidosis, and acute non-fulminant myocarditis
- Source :
- Int J Cardiol Heart Vasc
- Publication Year :
- 2023
- Publisher :
- Elsevier, 2023.
-
Abstract
- BACKGROUND: Giant cell myocarditis (GCM) and cardiac sarcoidosis (CS) are, in contrast to acute non-fulminant myocarditis (ANFM), rare inflammatory diseases of the myocardium with poor prognosis. Although echocardiography is the first-line diagnostic tool in these patients, their echocardiographic appearance has so far not been systematically studied. METHODS: We assessed a total of 71 patients with endomyocardial biopsy-proven GCM (n = 21), and CS (n = 25), as well as magnetic resonance-verified ANFM (n = 25). All echocardiographic examinations, performed upon clinical presentation, were reanalysed according to current guidelines including a detailed assessment of right ventricular (RV) dysfunction. RESULTS: In comparison with ANFM, patients with either GCM or CS were older (mean age (±SD) 55 ± 12 or 53 ± 8 vs 25 ± 8 years), more often of female gender (52% or 24% vs 8%), had more severe clinical symptoms and higher natriuretic peptide levels. For both GCM and CS, echocardiography revealed more frequently signs of left ventricular (LV) dysfunction in form of a reduced ejection fraction (p
- Subjects :
- Original Paper
Cardiology and Cardiovascular Medicine
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Int J Cardiol Heart Vasc
- Accession number :
- edsair.doi.dedup.....8af1f324d77826dde59d9f55c9d82f97