Association of chronic renal insufficiency with in-hospital outcomes after percutaneous coronary intervention

Background The association of chronic renal insufficiency with outcomes after percutaneous coronary intervention ( PCI ) in the current era of drug‐eluting stents and modern antithrombotic therapy has not been well characterized. Methods and Results We queried the 2007–2011 Nationwide Inpatient Sample databases to identify all patients aged ≥18 years who underwent PCI . Multivariable logistic regression was used to compare in‐hospital outcomes among patients with chronic kidney disease ( CKD ), patients with end‐stage renal disease ( ESRD ), and those without CKD or ESRD . Of 3 187 404 patients who underwent PCI , 89% had no CKD / ESRD ; 8.6% had CKD ; and 2.4% had ESRD . Compared to patients with no CKD / ESRD , patients with CKD and patients with ESRD had higher in‐hospital mortality (1.4% versus 2.7% versus 4.4%, respectively; adjusted odds ratio for CKD 1.15, 95% CI 1.12 to 1.19, P ESRD 2.29, 95% CI 2.19 to 2.40, P CKD 1.21, 95% CI 1.18 to 1.23, P ESRD 1.27, 95% CI 1.23 to 1.32, P P P PCI for acute coronary syndrome or stable ischemic heart disease. Conclusions In patients undergoing PCI , chronic renal insufficiency is associated with higher in‐hospital mortality, higher postprocedure hemorrhage, longer average length of stay, and higher average hospital charges.