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Antioxidant activity of whole grain highland hull-less barley and its effect on liver protein expression profiles in rats fed with high-fat diets
- Source :
- European journal of nutrition. 57(6)
- Publication Year :
- 2016
-
Abstract
- Whole grain exhibits potential for regulating lipid levels, possibly because of its antioxidant activity. This study aims to investigate the antioxidant activity of whole grain highland hull-less barley (WHLB) and its effect on liver protein expression profiles in rats fed with high-fat diets. Antioxidant activity of WHLB was investigated in vitro by analyzing phenolic and pentosan contents and oxygen radical absorbance capacity (ORAC). Proteins involved in lipid regulation were investigated in vivo by analyzing liver protein expression profiles in Sprague–Dawley rats fed with high-fat diet (HFD) with or without WHLB. WHLB possessed high total phenolic content (259.90 mg/100 g), total pentosan content (10.74 g/100 g), and ORAC values (418.05 ± 5.65 μmol/g). Rats fed with WHLB diet exhibited significantly (P
- Subjects :
- 0301 basic medicine
Antioxidant
Oxygen radical absorbance capacity
medicine.medical_treatment
Medicine (miscellaneous)
Biology
Diet, High-Fat
Antioxidants
Rats, Sprague-Dawley
03 medical and health sciences
0404 agricultural biotechnology
In vivo
Heat shock protein
medicine
Animals
education
education.field_of_study
Whole Grains
Nutrition and Dietetics
Lipid metabolism
Hordeum
04 agricultural and veterinary sciences
Lipid Metabolism
040401 food science
In vitro
Rats
030104 developmental biology
Phosphatidylethanolamine binding protein 1
Biochemistry
Liver
HSP60
Subjects
Details
- ISSN :
- 14366215
- Volume :
- 57
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- European journal of nutrition
- Accession number :
- edsair.doi.dedup.....8abb66158c41905d6635fd5070e00c62